We routinely prepare long (30-60 aa) to very long peptides up to a maximum length of approximately 100 aa. Because overall yield decreases exponentially with increasing length, synthesis and downstream processing times may increase significantly for longer sequences.
Many peptides of length over 40 aa have raised important research interest and their syntheses remains challenging. We have been manufacturing peptides > 40 aa with consistent high potency biological activity for many years.
This unique peptide grade includes an additional purification step following standard reversed-phase HPLC elution. It was developed by Genosphere Biotechnologies in collaboration with several research groups using our peptides in cell culture assays. It has been tested with a large number of cell types and exhibits no detectable cytotoxicity commonly associated with standard peptides at higher concentrations.
It has also proven to yield peptides with high activity in sensitive biochemical assays. Another noteworthy feature is a considerably increased stability of the peptides in aqueous solutions.