Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p) ppGpp. Czech, L. et al. (2022). Nature Communications 13, 1069.
Keywords: nucleotide-based second messengers, (p)ppGpp, signal recognition particle , SRP
An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity towards the autophagy-related hATG8 proteins. Brennan, A. et al. (2022). Journal of Biological Chemistry 298, p.101514.
Keywords: AIM; SQSTM1/p62; amyotrophic lateral sclerosis; autophagy; hATG8.
Synthetic Melanin Acts as Efficient Peptide Carrier in Cancer Vaccine Strategy. Cuzzubbo, S. et al. (2022). International Journal of Molecular Sciences 23, p14975.
Keywords: melanin; L-DOPA; cancer vaccine; adjuvant; nanoparticles; carrier; delivery system; peptide vaccine; dendritic cells; Langerhans cells.
PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders. Manso, J. A. et al. (2022). Cellular and Molecular Life Sciences 79, p131.
Keywords: Immunology, Pyogenic arthritis, pyoderma gangrenosum, myeloid-related proteinemia inflammatory syndrome, PAPA, PAMI, Auto-inflammation, LYP, PSTPIP1, F-BAR domain
Nardin, C., et al. (2021) Cancers, 13(20), p.5062.
Keywords: photosensitization, nitric oxide, purinergic signaling, calcium signaling
Elena‐Real, C.A., et al. (2021) The Plant Journal, 106(1), pp.74-85.
Keywords: 14-3-3 protein family; Arabidopsis; ITC; NMR; cytochrome c; programmed cell death.
Shorrocks, A.M.K., et al. (2021) Nature communications, 12(1), pp.1-15.
Campion, R., et al. (2021) Biochemical Journal, 478(24), pp.4153-4167.
Keywords: Saccharomyces cerevisiae; aging; mitochondria; molecular chaperones.
Rapid viscoelastic changes are a hallmark of early leukocyte activation.
Zak, A., et al. (2021) Biophysical Journal, 120(9), pp.1692-1704.
Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R.
Gellrich, A., et al. (2021) Frontiers in molecular biosciences, 8, 702341
Keywords: metalloprotease, meprin, sheddase, IL-6, CD99, APP, ADAM
Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule.
Cabrero, P., et al. (2020) Proceedings of the National Academy of Sciences, 117 (3) 1779-1787
Keywords: Drosophila melanogaster; Malpighian tubule; Xenopus oocyte; aquaporin; stellate cell
Benninghaus, V.A., et al. (2020) Journal of experimental botany, 71, pp.1278-1293.
Keywords: Articulated laticifers, barnase/barstar, differentially accumulated proteins, latex-non-exuding phenotype, metabolomics, proteomics, Taraxacum koksaghyz
Ramadan, R., et al. (2020) Frontiers in Pharmacology, 11, 212
Keywords: atherosclerosis, endothelial damage, ionizing radiation, connexin43 hemichannels, TAT-Gap19
Ultrastructural characterization of mitochondrial damage in experimental autoimmune neuritis.
Muke, I., et al. (2020) Journal of Neuroimmunology, 343, p.577218.
Keywords: Schwann cell, axon, mitochondria, neuritis, neuroinflammation ;
Role of SrtA in Pathogenicity of Staphylococcus lugdunensis
Hussain, M., et al. (2020) Microorganisms, 8(12), p.1975.
Keywords: LPXTG; Staphylococcus lugdunensis; sortase A; surface proteins.
Benoit, S., et al. (2020) Nutrients, 12(5), p.1497.
Keywords: milk bioactive peptide; α-Casozepine; anxiolytic; proteolytic fragments; anxiety; neuronal activity modulation; c-Fos
Sogues, A., et al. (2020) Nature communications, 11(1), pp.1-14.
Maurer, G.W., et al. (2020) PLoS genetics, 16(4), p.e1008727.
Keywords: human 22q11.2 deletion syndrome ; 22q11.2 DS ; schizophrenia ; sleep ; gene LZTR1 ; night owl ; nowl ; Drosophila ; Neurofibromin-1 deficiency ; Nf1 ; GABA signaling ; metabolic homeostasis
The adjuvant effect of melanin is superior to incomplete Freund’s adjuvant in subunit/peptide vaccines in mice. Cuzzubbo, S., et al. (2020) Cancer Immunology, Immunotherapy, 69(12), pp.2501-2512.
Keywords: Cancer vaccine, Immunotherapy, Synthetic melanin, Neoepitope mAdpgk, PD1, Peptide vaccine, Adjuvant, TLR9 agonist, CD8 + T-cell responses, MC38 model,
Structure of the Lifeact–F-actin complex.
Belyy, A et al. (2020) PLoS biology, 18(11), p.e3000925.
Keywords: Actin-binding peptide ; Lifeact–F-actin complex; cryo-EM, electron cryo-microscopy; F-actin, filamentous actin; cofilin ; myosin ; actin-binding toxins, ; TccC3HVR ; TccC3
Meprin β: A novel regulator of blood–brain barrier integrity.
Gindorf, M., et al. (2020) Journal of Cerebral Blood Flow & Metabolism, 41(1), pp.31-44.
Keywords: Blood–brain barrier, meprin β, tight junctions, brain endothelium, brain water content, metalloprotease, Mep1b
Jordan, P.M., et al. (2020) Cell reports, 33(2), p.108247
Keywords: lipid mediator, specialized pro-resolving mediators, lipoxygenase, inflammation, pore-forming toxin, α-hemolysin, Staphylococcus aureus
Deciphering CD4+ T cell specificity using novel MHC-TCR chimeric receptors.
Kisielow, J., et al. (2019) Nature immunology, 20(5), pp 652-662
Keywords: αβ T cell cognate peptides ; αβ T cell antigen receptors ; TCRs ; natural epitopes of CD4+ T cells ; peptide vaccination ; tumor-infiltrating lymphocytes
del Rio-Moreno, et al. (2019) Translational Research, 211, pp.147-160.
Keywords: tumor pathologies; SST1-5; somatostatin receptor 5 variant with 4 transmembrane domains; hepatocellular carcinoma; neuroendocrine tumor ; SST5TMD4-derived peptides ; somatostatin receptor subtype-5 ; truncated variant
MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.
Leimbacher, P.A., et al. (2019) Molecular cell, 74(3), pp 571-583
doi l Europe PMC
Keywords: MDC1 TOPBP1 complex ; casein kinase 2 ; CK2 ; DNA damage response ; DSBs in mitosis ; mitotic radiosensitivity ; chromosomal instability ; micronuclei formation ; chromosome end-to-end fusions.
Montaldo, N.P., et al. (2019) Nature communications, 10(1), pp.1-13.
Keywords: Actively transcribing chromatin; RNA pol II; Elongator complex; ELP1 subunit; aberrantly methylated DNA bases; 7-methylguanine; 3-methyladenine; Base excision repair; BER; alkyladenine DNA glycosylase; AAG; aberrant DNA bases
Synthetic peptides as a novel approach for detecting antibodies against sand fly saliva.
Sima, M., et al. (2019) PLoS neglected tropical diseases, 13(1), p.e0007078.
Keywords: Leishmania transmission, salivary antigens, Phlebotomus orientalis, Leishmania donovani, yellow-related protein, ParSP25-like protein.
Correia, S.I., et al. (2019) Frontiers in Plant Science, 10, p.438.
Keywords: Somatic embryogenesis induction ; somatic embryo development ; SpoU rRNA methylase family ; tamarillo; Solanaceae family ; plant morphogenesis
A Chemical Screen Identifies Compounds Limiting the Toxicity of C9ORF72 Dipeptide Repeats.
Corman, A., et al. (2019) Cell chemical biology, 26(2), pp 235-243
Keywords: ALS; BET Bromodomain; C9ORF72; arginine-rich peptides; chemical screen; dipeptide repeat proteins; nucleolar stress; sodium phenylbutyrate; zebrafish; poly(PR) peptides; non-ATG translation; dipeptide repeats; DPRs; HDAC inhibitors; PFI-1.
Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes.
Peters, F., et al. (2019) The FASEB Journal, 33(6), pp 7490-7504
Keywords: chronic intestinal inflammation; meprin β; protease; human meprin heterodimers; meprin α / meprin β-enzyme complex; meprin-knockout mice.
SIPA1L2 controls trafficking and signaling of TrkB-containing amphisomes at presynaptic terminals.
Andres-Alonso, M., et al. (2019) Nature Communications, 10(1):5448
Keywords: Amphisomes, autophagy pathway, autophagosomes, endosomes, neurons BDNF/TrkB, RapGAP, dynein motor, hippocampal neurons, presynaptic plasticity
Liu, D., et al. (2019) Mitochondrion, 47, pp.64-75.
Keywords: phosphodiesterase ; cAMP-degrading enzymes ; Calcium ; cAMP ; Mitochondrial membrane potential ; rodent cardiac mitochondria ; PDE2 transgenic mice ; oxidative phosphorylation ; subsarcolemmal mitochondria
Jacoberger-Foissac, C., et al. (2019) International journal of pharmaceutics, 562, pp 342-350
Keywords: Liposome ; Therapeutic vaccination ; Cancer vaccine; Adjuvant ; PRR agonists ; Peptide-based vaccine ; CD4 epitope peptide ; CD8 tumor-specific epitope peptide ; Pattern recognition receptors ; HA influenza virus peptide ; HPV16 E7 oncoprotein peptide; TLR4, TLR2/6 , NOD1 agonists
Manso, J.A., et al. (2019) Structure, 27(6), pp.952-964.
Keywords: hemidesmosomes ; integrin α6β4 and BP230 ; β4 – BP230 Crystal structure; FnIII domains ; cell adhesion ; keratinocytes plakins ; intermediate filaments.
Malbon, A.J., et al. (2019) Viruses, 11(12), p.1144.
Keywords: feline infectious peritonitis; feline coronavirus; hepatocytes; cardiomyocytes; inflammatory cytokines; pathogenesis; systemic inflammatory response, IL-1β, IL-6, TNF-α
Delvaeye T., et al. (2019) Scientific reports, 9(1), pp.1-12.
Keywords: Cx43 hemichannels; TAT-Gap19; TAT-CT9; Gap27; renal vascular permeability ; TNF-induced SIRS; tumour necrosis factor; systemic inflammatory response syndrome
Exotoxins from Staphylococcus aureus activate 5-lipoxygenase and induce leukotriene biosynthesis.
Romp, E., et al. (2019) Cellular and Molecular Life Sciences, 77(19), pp.3841-3858.
Keywords: 5-Lipoxygenase; Exotoxins; Leukotriene; Phenol-soluble modulins; Staphylococcus aureus, neutrophil infiltration, infectious inflammation, chemotactic, LTB4, 5-LOX, pore-forming toxin α-hemolysin, PSM Peptides
The nitrogen regulator PipX acts in cis to prevent operon polarity.
Cantos, R., et al. (2019) Environmental microbiology reports, 11(4), pp.495-507.
Keywords: Cyanobacteria, Bicistronic pipXY operon, PipX , NusG, TLD/KOW domain, pipY expression, PipX-PipY stoechiometry
The SRP signal sequence of KdpD.
Pross, E. and Kuhn, A. (2019) Scientific Reports, 9(1), p.8717.
Keywords: Walker A motif; KdpD signal sequence; ATP binding sites; cytoplasmic signal recognition particle; SRP receptor protein FtsY.
Qu, Y., et al. (2019) eLife, 8, e50319
Keywords: ARF activator Efa6, Cortical collapse factors, Drosophila Efa6, MT elimination domain, axon growth regulation, MTED
Zandawala, M. et al. (2018) Cellular and Molecular Life Sciences, 75(6), pp.1099-1115.
Keywords: Diuretic hormone 44 ; Corticotropin-releasing factor-like diuretic hormone ; Leucokinin ; Peptide hormones ; Stress resistance
Host-Polarized Cell Growth in Animal Symbionts.
Pende, N. et al. (2018) Current biology, 28(7), pp.1039-1051.
Keywords: Cell growth ; cell division ; cell shape ; symbiosis ; peptidoglycan ; MreB ; FtsZ ; Gammaproteobacteria
Sajic, M. et al. (2018) Journal of neuroinflammation, 15(1), p.61.
Keywords: Experimental autoimmune neuritis (EAN) ; Phototoxic damage ; In vivo Confocal imaging ; Mitochondrial ; Small axons ; Pain ; Neuropathy
Barreau, K. et al. (2018) PloS one, 13(8), p.e0201578.
Keywords: neurodegenerative diseases ; rat neural stem cells
Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling.
Vacca, B. et al. (2018) Scientific reports, 8(1), p.1204.
Keywords: Tight junctions, junctional barriers, semipermeable paracellular barriers, junctional signalling mechanisms, JNK, c-Jun N-terminal Kinase, AP1, ZONAB, YAP/TAZ, plaque proteins, cytoskeletal linkers, occludin, tricellulin, MarvelD3, junctional MARVEL domain, junctional tetraspan transmembrane proteins, epithelial stress response, eye morphogenesis, neural crest, Xenopus embryogenesis, early vertebrate development
Lelle, M. et al. (2018) International Journal of Peptide Research and Therapeutics, 24(3), pp.355-367.
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Keywords: Cell-penetrating peptide ; Multivalency ; Drug-peptide conjugate ; MDR ; Doxorubicin ; Drug resistance
Walrave, L. et al. (2018) Glia, 66(8), pp.1788-1804.
Keywords: TAT-Gap19; astrocytes; connexin43 hemichannels; pilocarpine; seizures
Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition.
Elena-Real, C.A. et al. (2018) Cell death & disease, 9(3), p.365.
Rodriguez-Fernandez, S. et al. (2018) Frontiers in immunology, 9, p.253.
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Stewart, L. et al. (2018) Clinical and experimental immunology, 194(2), p.153.
Keywords: Bacteroides fragilis ; autoimmune disease; coeliac; multiple sclerosis; rheumatoid arthritis; ubiquitin; ulcerative colitis; BfUbb protein
The Hebeloma cylindrosporum HcPT2 Pi transporter plays a key role in ectomycorrhizal symbiosis.
Becquer, A. et al. (2018) New Phytologist, 220(4), pp.1185-1199.
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Keywords: Pinus pinaster; Hebeloma cylindrosporum; 32P labeling; RNA interference; X-ray fluorescence mapping; ectomycorrhizal fungus; overexpression; phosphate transporter; symbiotic interface; inorganic phosphate; Hartig net; HcPT2; ectomycorrhizal symbiosis
Belyy, A. et al. (2018) Chemistry, 293(51), pp.19785-19796.
Keywords: ExoY; Pseudomonas aeruginosa; F-actin; bacterial toxin; confocal microscopy; cyclic nucleotide; protein cross-linking; protein-protein interaction; type III secretion system; nucleotidyl cyclase; 3′5′-cyclic nucleoside monophosphates
A secreted antibacterial neuropeptide shapes the microbiome of Hydra.
Augustin, R. et al. (2017) Nature communications, 8(1), p.698.
Keywords: Colonization of body epithelial surfaces, sensory neurons, ganglion neurons, ectodermal epithelium, hydra, Cnidaria, neuropeptides, antibacterial, microbiome, NDA-1, reduction of Gram-positive bacteria, Gram-negative Curvibacter sp, β-Proteobacteria, nerve cells, homeostasis, holobiont, biologically active peptides, corals, jellyfishes, polyps, bilateria, metazoans, microbiota, bacteroidetes, antimicrobial
Ovchinnikov, K.V. et al. (2017) Frontiers in microbiology, 8, p.774.
Keywords: enterocin K1, EntK1, enterocin EJ97, EntEJ97, LsbB, bacteriocins, lactococci, Enterococcus faecium, nosocomial multidrug resistant, rseP, stress response, Zn dependent protease, Streptococcus pneumoniae, synthetic ComS peptide
Bedau, T. et al. (2017) The FASEB Journal, 31(3), p.1226
Keywords: Adhesion molecule CD99 ; Transendothelial migration ; TEM assay ; Metalloprotease meprin β ; γ-secretase ; Intramembrane proteolysis ; Tissue remodeling ; Inflammation ; Lewis lung carcinoma cells ; Mep1b−/− mice
Weaver, R.E. et al. (2017). Biochem Pharmacol. , 127, pp. 71-81
Keywords: Parathyroid hormone ; PTH ; GPCR ; Agonist ; Receptor ; TIP39 ; Cancer treatment
Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase.
Abplanalp, J. et al. (2017) Nature communications, 8(1), p.2055.
Keywords: antibodies, histone post-translational modifications, hydrolases, ADP-ribosylation, ARTD1, PARP1, PARG, ARH3, poly-ADP-ribosylation, PARylation, mono-ADP-ribosylation, hydrogen peroxide stress, ADP-ribosylome, nicotinamide adenine dinucleotide
Altered Protein Interactions of the Endogenous Interactome of PTPIP51 towards MAPK Signaling.
Brobeil, A. et al. (2017) Biomolecules, 7(3), p.55.
Keywords: Protein–protein interactions, protein tyrosine phosphatase interacting protein 51, PTPIP51, LDC-3, regulation of the endogenous interactome, siRNA, human keratinocytes, HaCaT cells, mitogen activated protein kinase, MAPK, Raf-1, protein scaffold 14-3-3, protein tyrosine phosphatase 1B, PTP1B, dysregulated signal transduction, proliferation, differentiation, apoptosis, basal cell carcinoma, squamous cell carcinoma, acute myeloid leukemia, malignant blasts, EGFR, insulin receptor, nuclear factor κB, transcription factors, NFκB, neurophysin, CGI-99, Nuf2, DGKα, c-Src, mitotic protein complex, calcium homeostasis
Phytochelatin synthesis in response to Hg uptake in aquatic plants near a chlor-alkali factory.
Turull, M. et al. (2017) Chemosphere, 176, pp.74-80.
Keywords: Ceratophyllum demersum; Mercury; Myriophyllum spicatum; Phytochelatins
Kilkenny, M.L. et al. (2017) Open biology, 7(11), p.170217.
Keywords: Ctf4-interacting peptide (CIP) motif, DNA replication, replisome, protein–protein interactions, protein–DNA interactions, DNA polymerase, protein hub, Ctf4, chromosome transmission fidelity 4, DNA helicase, Cdc45-MCM-GINS, CTF4 orthologue, AND-1, DNA polymerase α, Pol α / primase, helicase–nuclease Dna2, SepB domain, HMG box, lagging-strand, replication fork, human replisome, Chl1, rDNA, Tof2
Esquerré, M. et al. (2017) PloS one, 12(3), e0174038.
Keywords: HPV-16 ; Mouse models ; T cells Cytotoxic T cells ; Vaccination and immunization ; Human papillomavirus infection ; Immunologic adjuvants ; Cancer treatment
A role for the metalloprotease invadolysin in insulin signaling and adipogenesis.
Chang, C.W. et al. (2017) Biological Chemistry, 398(3), pp.373-393.
Keywords: adipogenesis; insulin signaling; lipid droplets; metalloprotease ; Invadolysin ; metazoans ; Drosophila ; glycogen storage ; autophagy
In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface.
Bestgen, B. et al. (2017) Pharmaceuticals, 10(1), p.16.
Keywords: cell death; cyclic peptides; protein kinase CK2; protein–protein interaction; subunit interface
Structural Insight into BLM Recognition by TopBP1.
Sun, L. et al. (2017) Structure, 25(10), pp.1582-1588.
Keywords: Topoisomerase IIβ binding protein 1, TopBP1, BRCT5, Bloom syndrome helicase, BLM, pSer-binding pocket, DNA damage mediator, MDC1, phosphopeptide interactions, X-ray crystallography, fluorescence polarization, BRCT
Serological Analysis of Tuberculosis in Goats by Use of the Enferplex Caprine TB Multiplex Test.
O’Brien. et al. (2017) Clinical and Vaccine Immunology, 24(2), e00518-16.
Keywords: tuberculosis, antibodies, goats, Mycobacterium avium subsp. paratuberculosis, Mycobacterium bovis, serologic tests, goat diseases diagnosis, veterinary tuberculosis
Synthetic melanin bound to subunit vaccine antigens significantly enhances CD8+ T-cell responses.
Carpentier, A.F. et al. (2017) PloS one, 12(7), p.e0181403.
Keywords: melanin, Dopa, tumor, dermatopathic lymphadenopathy, fungal skin disease, melanosomes, memory CD8+ T-cells, TLR9, ovalbumin, TLR, Ephrin-A2, L-Selectin
Labella, J.I. et al. (2017) Frontiers in microbiology, 8, p.1244.
Keywords: Synechococcus elongatus, nitrogen regulation, cyanobacteria, 2-oxoglutarate receptor, 2-OG, global transcriptional regulator, NtcA, co-activator PipX, signal transducer PII, nitrogen and carbon balance, PlmA, PipY, bicistronic operon pipXY, COG0325 proteins, amino/keto acid homeostasis, PLP-related phenotypes, PLP-holoenzymes, synthetic lethality, cysK, autotrophic growth, GS-GOGAT cycle.
Ruiz-Santaquiteria, M. et al. (2017) European journal of medicinal chemistry, 135, pp.49-59.
Keywords: Peptides, Helix stabilization, Protein-protein interactions, Trypanothione reductase, Leishmania infantum, Cell-penetrating peptides, amide-bridged cyclic peptides, lactam peptides, helical turn, Li-TryR
Benoit, S. et al. (2017) Journal of Functional Foods, 38, pp.464-473.
doi l Europe PMC
Keywords: α-Casozepine, α-CZP, bioactive peptide, milk casein, anxiolytic, c-Fos, marker of neuronal activity, diazepam, benzodiazepine, hippocampus, accumbens nucleus, hypothalamus, amygdala, prefrontal cortex, anxiety-inducing situation, tryptic hydrolysate of bovine αs1 casein, GABA, anxiety
Protoplast swelling and hypocotyl growth depend on different auxin signaling pathways.
Dahlke, R.I. et al. (2017) Plant physiology, 175(2), pp.982-994.
Keywords: AtABP1 peptide, Arabidopsis thaliana, transport inhibitor response1, auxin signaling f-box protein, TIR1 / AFB, auxin binding protein1, ABP1, hypocotyl growth
Bedau, T. et al. (2017) Oncotarget, 8(33), p.54873.
Keywords: peptide, transendothelial cell migration, inflammation, metastasis, adhesion molecule, CD99, extravasation, metalloprotease, meprin β, pro-inflammatory, lung cancer, proteolytic shedding, Src phosphorylation,
Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.
O’Brien, D.P. et al. (2017) PLoS biology, 15(12), p.e2004486.
Keywords: Calmodulin, response to calcium, adenylate cyclase toxin, CyaA, calmodulin binding, cAMP release, AC conformational disorder, calmodulin-activated enzyme, Bordetella pertussis, virulence factor, CaM, hydrogen/deuterium exchange mass spectrometry, disorder-to-order transition, HDX-MS, SAXS, synchrotron radiation circular dichroism, catalytic loop flexibility, long-range allosteric effects.
Bessette, C. et al. (2016) Molecular nutrition & food research 60(4), 823-33
Keywords: Milk bioactive peptide ; Mucus ; Intestinal protection ; Functional food ; Inflammatory bowel disease
Poosti, F. et al. (2016) Oncotarget, 7(34), pp.54240-54252.
Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis.
Daskalov, A. et al. (2016) Proceedings of the National Academy of Sciences 113(10), 2720-5.
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Unraveling flp-11/flp-32 dichotomy in nematodes.
Atkinson, L.E. et al. (2016) International Journal for Parasitology, 46(11), pp.723-736.
doi l Europe PMC
Keywords: FLP-11; FLP-32; FMRFamide-like peptide; Nematode; Neuropeptide; Neuropeptide signalling; flp-11; flp-32
TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
Hoffmann, S. et al. (2016) The Journal of cell biology 212(1), pp.63-75.
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Keywords: Proliferating Cell Nuclear Antigen ; TRAIP protein, human ; Ubiquitin-Protein Ligases
(I) Pharmacological profiling of a novel modulator of the α7 nicotinic receptor: Blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer brains.
Garcia-Ratés, S. et al. (2016) Neuropharmacology 105, pp.487-499.
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AMP-activated protein kinase upregulates MAP kinase interacting serine/threonine kinase 1a-dependent phosphorylation of eukaryotic translation initiation factor 4E.
Zhu, X. et al. (2016) Journal of Biological Chemistry, 291(33), pp.17020-17027.
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Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA.
Königer, V. et al. (2016) Nature Microbiology, 2, p.16188.
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Nuclear fallout provides a new link between aPKC and polarized cell trafficking.
Calero-Cuenca, F.J. et al. (2016) BMC biology 14(1), p.32
Keywords: aPKC; Cell polarity; Cell trafficking; Nuclear fallout
Prabhu, S. A. et al. (2015) Molecular biology reports 42(6), pp.1123-1138.
Keywords: Chemical deglycosylation; Confocal immunolocalization; Peptide mass fingerprinting; Plant–pathogen interaction; Quantitative real-time PCR; Two-dimensional gel electrophoresis
Serna M et al. (2015) Journal of Cell Science 128(9), pp. 1824-1834
Keywords: Tubulin; Protein degradation; Chaperones; Folding cofactors; Microtubule
EMMPRIN regulates β1 integrin-mediated adhesion through Kindlin-3 in human melanoma cells.
Delyon J et al. (2015) Experimental dermatology, 24(6), pp. 443-448
Keywords: EMMPRIN; Kindlin-3; cell adhesion; melanoma; β1 integrin
Blackford A N et al. (2015) Mol cell 57, 1133-1141
Identification of a Taraxacum brevicorniculatum rubber elongation factor protein that is localized on rubber particles and promotes rubber biosynthesis.
Laibach N et al. (2015) The Plant J 82, 609-620.
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Use of autoantigen-loaded phosphatidylserine-liposomes to arrest autoimmunity in type 1 diabetes.
Pujol-Autonell I et al. (2015) PloS ONE 10.6, e0127057
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Influence of Ligands in Metal Nanoparticle Electrophoresis for the Fabrication of Biofunctional Coatings.
Streich C et al. (2015) Appl Surface Sci 348, 92–99
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Carbon nanotubes and graphene modified screen-printed carbon electrodes as sensitive sensors for the determination of phytochelatins in plants using liquid chromatography with amperometric detection.
Dago A et al. (2015) J Chromatography A 1409, 210–217
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Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes.
Ivy JR et al. (2015) PLoS ONE 10.8, e0134620
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New insight into the structure and function of Hfq C-terminus.
Fortas E et al. (2015) Bioscience Rep 35 (2).
Memory and PTPIP51 – A new protein in hippocampus and cerebellum.
Brobeil A et al. (2015) Mol Cell Neurosci 64, 61-73.
Signal Transduction by a Fungal NOD-Like Receptor Based on Propagation of a Prion Amyloid Fold.
Daskalov A et al. (2015) PLoS Biol 13, e1002059
The adhesive properties of the Staphylococcus lugdunensis multifunctional autolysin AtlL and its role in biofilm formation and internalization.
Hussain M et al. (2015) Int J Med Microbiol 305, 129-39
β-Casein(94-123)-derived peptides differently modulate production of mucins in intestinal goblet cells.
Plaisancié P et al. (2015) J Dairy Res 82, 36-46
Full membrane spanning self-assembled monolayers as model systems for UHV-based studies of cell-penetrating peptides.
Franz J et al. (2015) Biointerphases 10(1) , 019009.
Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.
Fahrenkamp D et al. (2015) Cell Communication and Signaling 13, 10
Chloride channels in stellate cells are essential for uniquely high secretion rates in neuropeptide-stimulated Drosophila diuresis.
Cabrero P et al. (2014) Proc Natl Acad Sci U S A 111,14301-14306.
Escherichia coli Common Pilus (ECP) Targets Arabinosyl Residues in Plant Cell Walls to Mediate Adhesion to Fresh Produce Plants.
Rossez Y et al. (2014) J Biol Chem 289, 34349.
The role of metalloproteinase ADAM17 in regulating ICOS ligand-mediated humoral immune responses.
Marczynska J et al. (2014) J Immunol 193, 2753-63
Identification of a mitochondrial external NADPH dehydrogenase by overexpression in transgenic Nicotiana sylvestris.
Michalecka AM et al. (2014) Plant J 37, 415-25.
CD31 is a key coinhibitory receptor in the development of immunogenic dendritic cells.
Clement M et al. (2014) Proc Natl Acad Sci U S A 111, E1101-10.
An ancient oxidoreductase making differential use of its cofactors.
D Blüher et al. (2014) Biol Chem 395, 855–869
[The acidic C-terminal tail of the GyrA subunit moderates the DNA supercoiling activity of Bacillus subtilis gyrase.
Lanz MA et al. (2014) J Biol Chem 289, 12275-85
A polymerase chain reaction and enzyme linked immunosorbent assay based approach for diagnosis and differentiation between vaccinated and infected cattle with Mycobacterium bovis.
Sabry M et al. (2014) J Pharm Bioallied Sci 6, 115-21
Study on Aβ34 biology and detection in transgenic mice brains.
Caillava C et al. (2014) Neurobiol Aging 35, 1570-81
Novel cleavable cell-penetrating peptide-drug conjugates: synthesis and characterization.
Lelle M et al. (2014) J Pept Sci 20, 323-33
Effects of synthetic analogues of human opiorphin on rat brain opioid receptors.
Benyhe Z et al. (2014) J Physiol Pharmacol 65, 525-30
Arabidopsis Thaliana AXR4 Recombinant Protein Expression for Polyclonal Antibody Production
Norliza AB et al. (2014) Asian J of Plant Biol 1 , 34-38
Optimising and Evaluating the Characteristics of a Multiple Antigen ELISA for Detection of Mycobacterium bovis Infection in a Badger Vaccine Field Trial.
Aznar I et al. (2014) PloS one 9, e100139.
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