Custom Services
For Research
Our Services
Custom Peptide Synthesis
Our team of chemists can look back on many years of experience in the successful synthesis of numerous biologically active peptides, including :
•long peptides,
•hydrophobic sequences,
•structurally modified peptides,
•flurorescent, FRET, protein-peptide conjugates,
•unusual and non-natural amino-acids
Our Services
Custom Polyclonal Antibodies
Our established immunisation protocols & procedures have enabled us to deliver our customers with optimal, consistent quality antibodies for many years. And we are enjoying a long track record of successful antibodies as attested by the numerous published literature citations every year. Because we recognize that quality and reliability are central to our customers, we never let an antiserum go out unless it has a minimum good titer.
Genosphere Biotechnologies offers this unique guarantee to our customers for anti-peptide antibodies as well as for anti-protein antibodies services, provided sample requirements are fulfilled.
Our Services
Custom Gene Synthesis
Our gene synthesis team has many years experience in the fields of bioinformatics, molecular biology, and nucleic acid chemistry and we offer unconditionally guaranteed sequences, backed up by strong QC procedures.
We offer a complete range of genetic engineering services, from codon optimization, to subcloning, site-directed mutagenesis and large scale plasmid preparations
Our Services
Protein Expression and Purification
We start from the accession number of your protein of interest and we will express and purify your recombinant protein at research scale and affordable price.
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√ E. coli √ Yeast | √ Baculovirus-insect cells |
Welcome to our web site !
Genosphere Biotechnologies is your reliable, affordable quality services provider. Our experienced teams of organic chemists, biochemists and immunochemists are ready to support your projects.
Get to know Genosphere Biotechnologies !
We have gained the trust of many life science laboratories worldwide in the last two decades, we feel very confident in asking you to give us chance to convince you as well.
| Quick online quote: |
| ⇒ Custom peptide quote |
| ⇒ Custom antibodies quote |
| ⇒ Custom gene quote |
| ⇒ Other services quote |
How our customers are pushing back the frontiers
Founded in 1997, Genosphere Biotechnologies now enjoys thousands of literature Materials & Methods citations worldwide and contributes to numerous original Research & Development projects across all areas of life sciences. Find out more about some of these projects, several of which are destined to become a landmark in their field.
Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation. Martinez, M. et al. (2023). Nature Microbiology, 8(10), pp. 1896–1910.
A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum. Buitelaar, P.L. et al. (2024). Journal of Pharmaceutical and Biomedical Analysis, 243, p. 116108.
cAMP binding to closed pacemaker ion channels is cooperative. Kuschke, S. et al. (2024). Proceedings of the National Academy of Sciences, 121(9), p. e2315132121.
Small fiber integrity and axonal pathology in the rat model of experimental autoimmune neuritis. Renk, P. et al. (2024). Brain Communications, 6, p.59.
BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution. Tsukada, K. et al. (2024). Molecular Cell, 84(4), pp. 640-658.
Innovative peptide synthesis every day !
Your recombinant protein in just a few weeks !
From DNA to Purified Protein - Our 
Workflow
Sequence Design: To address issues related to codon usage bias, we offer codon optimization services, improving protein expression.
Gene Synthesis and Plasmid Cloning: We synthesize DNA and clone it into a high-copy plasmid.
Protein Expression and Optimization: We determine gene expression levels, analyze products, and offer scale-up.
Protein Purification: Utilizing affinity chromatography, ion exchange, and gel filtration, we purify and characterize proteins.
Optional Services:
• TAG removal
• Endotoxin elimination
• Scale-up fermentation and purification
► Get started: Contact us at protein@genosphere-
biotech.com with:
• Your gene or protein sequence or UniProt accession number.
• Your preferred expression system(s).
• The mg amount of recombinant protein needed (0.1 mg, 0.5 mg, 1 mg...).
• The purity level required (>80%; >90%).
Five Expression Systems: Choose from bacteria, yeast, insect cells, mammalian cells, or in vitro expression.
Affinity Tags: Customize with N-/C-terminal tags (e.g., GST, His6, His10, etc.).
Genosphere Biotechnologies : Custom Services for Research