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Amino Acids Basic Properties
Name, Abbreviations, Chemical classification, Relative Abundance, and Acid-Base properties of each of the natural amino acidsAmino acid.
Amino acid |
Codes |
Relative abundance (mole%) (1) |
MW (2) |
pKa (3) |
|
Parental |
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Glycine |
gly |
G |
8.3 |
57.05 |
|
Aliphatic |
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Proline |
pro |
P |
3.4 |
97.12 |
|
Alanine |
ala |
A |
9.4 |
71.09 |
|
Valine |
val |
V |
5.8 |
99.13 |
|
Leucine |
leu |
L |
10.7 |
113.08 |
|
Isoleucine |
ile |
I |
5.7 |
113.16 |
|
Aromatic |
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Phenylalanine |
phe |
F |
4.8 |
147.18 |
|
Tryptophan |
trp |
W |
1.1 |
186.21 |
|
Tyrosine |
tyr |
Y |
2.9 |
163.18 |
9.6 |
Histidine |
his |
H |
2.1 |
137.14 |
7.0 |
Sulfur |
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Cysteine |
cys |
C |
2.5 |
103.15 |
8.5 |
Methionine |
met |
M |
2.3 |
131.20 |
|
Hydroxyl |
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Serine |
ser |
S |
7.4 |
87.08 |
16 |
Threonine |
thr |
T |
5.5 |
101.11 |
16 |
Strongly acidic |
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Aspartic acid |
asp |
D |
4.6 |
115.09 |
4.7 |
Glutamic acid |
glu |
E |
5.3 |
129.16 |
4.7 |
Strongly basic |
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Lysine |
lys |
K |
5.6 |
128.17 |
10.2 |
Arginine |
arg |
R |
4.6 |
156.19 |
12 |
Amido |
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Aspargine |
asn |
N |
4.3 |
114.10 |
|
Glutamine |
gln |
Q |
3.7 |
128.13 |
|
(E. coli), hemoglobin & cytochrome c (human), glucagon (pig), ferridoxin (spinach), wool (sheep).
(2) Isotopic average of neutral amino acyl residu in a peptide bond.
(3) In peptides in aqueous solution. N-terminus: pKa=7.8 & C-terminus: pKa=3.7.